Sucrose Octanoate Ester (Sucrocide) is a 'soap' made with sugar and an 8 chain fatty acid. Its chemical properties are quite different from sucralose, I believe, even though both have a sugar group. Various octanoate compounds have been well studied (I use copper octanoate as a fungicide, it is organically certified). Sucralose is chlorinated sugar - the chlorine holds the sugar together, it tastes sweet but cannot be broken down in the body, it floats around in the blood and does who knows what until it gets excreted. In general, chlorinating a hydrocarbon or carbohydrate makes it more resistant to breakdown, and more toxic. But the sucrocide is a very mild soap, different from splenda.