Well, no theories, one caution...
Yep, I had a customer located in an area that took me through Pueblo, and I agree that it is a bit flat there! I would always talk to the county agricultural extension office about any farmland purchase I had in mind in CO. The reason I say so is because of WATER. Water rights are being sold to developers and municipalities at a very high rate these days throughout the state, and througout the West.
Not far from me is another water rights boundary, the Denver Water Board southwest bundary of the Arkansas watershed. A man I know that lives in literally the south western most house was watering his tiny container garden when he was served a summons to a water court, fined, and made to stop using a hose outside his house! And this is a 3 hour drive to Denver, this is a very rural area. It still galls me that someone around here must have called him in...
So no matter how humble your few acres, you need a steady irrigation water source, as the sun here will easily parch the top 4 to 6 inches of any soil and rainfall is not consistent enough. Certainly organic practices, especially MULCH and rotational grazing practices, will help you conserve water, as does raised bed gardening. So just make sure it's really sure about water, wells and all that, and don't trust the realtor to find out honestly for you. Lots of farms are being sold with "wells", but the real water source, stream flow rights, has already been sold away...
All that said, Colorado sure is a beautiful place, and every place you go to is unique in it's own way and beauty, and every place on Earth has it's unique problems, so good luck finding that dream farm with the mountian vista